National Institute of Molecular Biology and Biotechnology, UP Diliman
Together with the biotechnology institutes of
the University of the Philippines System in UP Manila and UP
Los Baños, UP Diliman’s National Institute of Molecular
Biology and Biotechnology (NIMBB) aims to promote biotechnology
for national development. NIMBB in UP Diliman is an academic
unit under the College of Science.
Aside from granting baccalaureate, masters and
doctorate degrees, the Institute is evolving to expand its linkages
with other academic or non-academic, private or public organizations/individuals
– expanding its horizon in thrusting biotechnology for
a diverse audience. Through this extension service, the Institute
also coordinates seminars, workshops and exhibits.
NIMBB is equipped with the necessary facilities
as well as the technical experts to engage in various biotechnology
projects. The Institute has the capacity to analyze, identify,
and purify genes, proteins and microbes. It is also capable
of using laboratory animals as source of cells for tissue culture
and as models of human diseases. Immunology research and DNA
vaccine production are also part of the Institute’s activities.
Facilities for delivering genes to plant, animal and bacterial
cells through physical, chemical or electrical methods are likewise
available.
Several laboratory processes and functions pertaining
to the use of highly specialized equipments are available as
extension service. The research activities of NIMBB are conducted
in its five laboratories:
- Laboratory of Molecular Cell Biology
projects:
- Axon Guidance and Neurite Extension
- Agouti-related Obesity
- Cloning of Developmental Control Genes
- Isolation and Analysis of Fluorescent Proteins From
Various Organisms
- Medical Biotechnology and Genome Research Laboratory
projects:
- Developing Gene Expression Systems for Recombinant
Antibody Production
- Dimerization Conditions for Antibodies
- Generation of Humanized Single Gene-encoded Antibodies
With Varied Effector Functions
- Developing Genetic Markers in Hatchery-bred Milkfish
(Chanos chanos forsskal), Hito (Clarias macrocephalus)
and Kanduli (Arius manilensis)
- Molecular Medicine and Biotechnology Laboratory
projects:
- Development of DNA Vaccines Against Dengue Virus
- Preliminary Immunogenicity of DNA Vaccines Against
Dengue
- DNA Immunization With Conserved and/or Promiscuous
B and T-helper Epitopes from Plasmodium falciparum
- Development of DNA Vaccines Against Hog Cholera (Classical
Swine Fever)
- Preclinical Evaluation of Safety of DNA Vaccines Against
Dengue and Malaria
- Molecular Microbiology Laboratory
projects:
- DNA-based Screening for Enzyme Producing Bacteria Bacillus
sp.
- DNA Sequence Analysis of the 16s rRNA and cyt b Genes
From Selected Wildlife Species Endemic to the Philippines
- DNA-based Approaches to Detection of Pathogens in Aquaculture
- Development of DNA-based Detection Procedures for Genetically
Modified Plants and Plant Products
- Protein Structure and Function Laboratory
projects:
- Cloning of Phenoloxidase, an Insect Enzyme Involved
in Melanin Synthesis
- Elucidation of Structure of Phenoloxidase
- Isolation of Peptide Inhibitions for Phenoloxidase
Contact details:
National Institute of Molecular Biology and Biotechnology
Albert Hall
Lakandula cor. Jacinto Sts.,
University of the Philippines – Diliman
1101 Quezon City
Tel. 927-7516 or 920-5301 to 99 local 7947
http://www.mbb.upd.edu.ph/index.htm